Complement C4 Test ₹650

The Complement C4 Test measures the level of Complement Component 4 (C4), an important protein of the immune system. It helps diagnose and monitor autoimmune diseases, evaluate immune system disorders, investigate recurrent infections, and assess diseases involving abnormal complement activation.

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Advanced Immunology Testing Available

Quick Details

Test Price ₹650

Fasting Required No

Sample Type Blood (Serum)

Report Time Same Day / 1 Working Day*

What is the Complement C4 Test?

The Complement C4 Test measures the amount of Complement Component 4 (C4) in your blood. C4 is part of the classical complement pathway, which plays a vital role in defending the body against infections and removing immune complexes. Abnormal C4 levels may be associated with Systemic Lupus Erythematosus (SLE), hereditary angioedema, autoimmune disorders, kidney diseases, or inherited complement deficiencies.

Who should take this test?

Individuals with suspected Systemic Lupus Erythematosus (SLE).
Patients with hereditary angioedema or recurrent unexplained swelling.
Individuals with autoimmune or inflammatory diseases.
Patients with kidney disorders such as lupus nephritis or glomerulonephritis.
People experiencing recurrent bacterial infections.
Doctor-recommended monitoring of complement system disorders.

Preparation & Test Process

Fasting

No fasting is generally required before this test.

Sample Type

A blood sample is collected from a vein in your arm.

Purpose

Evaluates Complement C4 levels to assess autoimmune diseases, complement deficiencies, and immune system function.

Important Note

Your doctor may also recommend Complement C3, CH50, ANA Profile, Anti-dsDNA, C1 Esterase Inhibitor, or kidney function tests for a complete evaluation.

Understanding Your Results

Low Complement C4 levels may indicate active lupus (SLE), hereditary angioedema, immune complex diseases, severe infections, or inherited complement deficiencies.

High Complement C4 levels may occur during acute inflammation, certain infections, obesity, or other inflammatory conditions.

Results should always be interpreted together with Complement C3, autoimmune antibody tests, kidney function tests, and your overall clinical condition.

FAQs – Complement C4 Test

It helps diagnose and monitor autoimmune diseases, hereditary angioedema, complement deficiencies, and immune-related disorders.

No. Fasting is generally not required before sample collection.

Measuring both Complement C3 and C4 provides a more complete assessment of complement pathway activity and helps diagnose autoimmune diseases and immune deficiencies.

Yes. Low Complement C4 levels are commonly associated with active lupus and hereditary angioedema, but results should always be interpreted with clinical findings and additional laboratory tests.

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Disclaimer: This page is for informational purposes only. Consult your doctor for medical advice. All tests processed with NABL-aligned quality standards.