What is the Celiac Disease Profile 1 (Basic)?

The Celiac Disease Profile 1 (Basic) is a screening panel that detects antibodies associated with Celiac Disease, an autoimmune condition in which the immune system reacts to gluten, damaging the lining of the small intestine. The panel commonly includes tests such as Tissue Transglutaminase (tTG) IgA and Total IgA (test components may vary by laboratory). It helps doctors determine whether further evaluation, including intestinal biopsy, may be necessary.

Who should take this test?

• Individuals with chronic diarrhea, bloating, or abdominal pain.
• Patients with unexplained weight loss or nutritional deficiencies.
• Children with delayed growth or poor weight gain.
• Individuals with a family history of Celiac Disease.
• Patients with autoimmune disorders such as Type 1 Diabetes or autoimmune thyroid disease.
• Doctor-recommended evaluation for suspected gluten sensitivity or Celiac Disease.

Preparation & Test Process

Understanding Your Results

Positive antibody results increase the likelihood of Celiac Disease and may require confirmation with additional testing, such as an intestinal biopsy, based on your doctor’s assessment.

Negative results reduce the likelihood of Celiac Disease but do not completely exclude the condition, particularly in individuals with IgA deficiency or those already following a gluten-free diet.

Results should always be interpreted together with symptoms, dietary history, family history, and your doctor’s clinical evaluation.

FAQs – Celiac Disease Profile 1 (Basic)