What is the AFB/TB MDR Detection (INH & RIF) – Hains Genotyping Test?

The Hain Line Probe Assay (LPA) is a molecular diagnostic test used to detect Mycobacterium tuberculosis and identify genetic mutations that cause resistance to Isoniazid (INH) and Rifampicin (RIF). These two drugs are the most important first-line anti-TB medications. Detecting resistance early helps doctors start the correct MDR-TB treatment regimen quickly.

Who should take this test?

• Patients diagnosed with tuberculosis (TB).
• Individuals suspected of having drug-resistant TB.
• Patients not responding to standard anti-TB therapy.
• People with recurrent TB infection.
• Doctor-advised evaluation for MDR-TB detection.

Preparation & Test Process

How to interpret results

The report indicates whether the TB bacteria are sensitive or resistant to key drugs such as Isoniazid (INH) and Rifampicin (RIF).

Drug resistance detected may indicate multi-drug resistant tuberculosis (MDR-TB).
No resistance detected suggests the bacteria are likely responsive to standard first-line TB treatment.

Results should always be interpreted by a physician or infectious disease specialist along with clinical findings and other TB tests.

FAQs – AFB/TB MDR Detection Test